Comparison of estimated glomerular filtration rate equations on prediction of mortality, kidney failure and acute kidney injury.

ABSTRACT:

Background

The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)ASR-NB2009 estimated glomerular filtration rate (eGFR) equation has shown substantial overestimation of GFR in Europeans, hence new equations have been developed. We examined the effect of introducing the European Kidney Function Consortium (EKFC) or Lund-Malmö revised (LMR) eGFR equations on KDIGO eGFR category classification in a large cohort. We compared the EKFC and LMR equations with the CKD-EPIASR-NB2009 formula in view of discriminative ability of all-cause mortality, kidney failure with replacement therapy (KFRT) and acute kidney injury (AKI) risks across eGFR categories.

Methods

Individuals aged ≥18 years with a serum creatinine measurement (December 2006-July 2024) at University Medical Cente

SUBMITTER: Veltkamp DMJ 

PROVIDER: S-EPMC12477466 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature