A meta-analysis of graft survival, patient survival and delayed graft function in first-time and repeat kidney transplants.

ABSTRACT:

Background

Previous evidence showed that while first-time kidney transplants (KT) typically yield better outcomes, repeat and subsequent transplants were associated with increased risks of graft failure and adverse patient outcomes, yet conflicting findings exist. The aim of this meta-analysis is to compare graft survival and delayed graft function (DGF) outcomes in first-time KT, repeat KT (regrafts) and subsequent KT.

Methods

Relevant studies were identified through comprehensive searches in PubMed, Web of Science, Cochrane Library, MEDLINE (Ovid) and Scopus until 8 October 2024. Primary outcomes include graft survival and DGF, compared with repeat and subsequent KT.

Results

The meta-analysis included a total of 16 studies. Analysis on long-term graft survival revea

SUBMITTER: Kanbay M 

PROVIDER: S-EPMC12477473 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature