Regional Mortality From Chronic Liver Diseases in African Countries Attributable to Hepatitis B Virus and Hepatitis C Virus Infections From 1990 to 2021 and Projections to 2030.

ABSTRACT:

Background

This study aims to explore the magnitude and temporal trend of the chronic liver disease (CLD) burden in Africa and examine the progress toward the global goal of eliminating CLD attributable to HBV and HCV by 2030.

Methods

Data from the Global Burden of Disease database were used to extract the mortality burden across 47 African countries between 1990 and 2021. The CLD burden from 2022 to 2030 was projected using the Bayesian age cohort model.

Results

In 2021, the number of CLD-related deaths and age-standardized death rates (ASDR) due to HBV were higher (81 074 deaths and 14.2 per 100 000) compared to HCV (60 717 and 11.2 per 100 000). Western Africa had the highest number of deaths from CLD caused by HBV (33 603) and HCV (19 583), whereas Central Africa

SUBMITTER: Ou TY 

PROVIDER: S-EPMC12477677 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature