Outcomes of transsphenoidal surgery in 34 small dogs with pituitary-dependent hypercortisolism.

ABSTRACT:

Objective

This study aimed to evaluate the clinical outcomes of transsphenoidal surgery (TSS) in dogs weighing < 15 kg with pituitary-dependent hypercortisolism (PDH).

Animals

The study included 34 dogs, each weighing < 15 kg, diagnosed with PDH, and undergoing TSS at our facility between 1999 and 2021.

Procedure

Postoperative assessments included fatal complications within 4 wk, the extent of mass resection, the duration of central diabetes insipidus, long-term survival, and duration of remission.

Results

Five dogs died within 4 wk after TSS. Complete resections were completed in 28 dogs, whereas 6 dogs underwent partial resection. Factors associated with partial resection included a higher pituitary-to-brain ratio (odds ratio: 112 705.8; P = 0.014). Th

SUBMITTER: Tanaka S 

PROVIDER: S-EPMC12477731 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature