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Human infections with highly pathogenic avian influenza A(H5N1) viruses in the United States from March 2024 to May 2025.


ABSTRACT: Between March 2024 and October 2024, 46 human cases of highly pathogenic avian influenza (HPAI) A(H5N1) had been detected in the United States. The persistent panzootic spread of HPAI A(H5N1) viruses and continued detection of human cases presents an ongoing threat to public health. In this study, between November 2024 and May 2025, an additional 24 cases have been reported for a total of 70 human cases of HPAI A(H5N1): 41 were exposed to dairy cows, 24 to commercial poultry, two to backyard poultry and three had an unidentified source of exposure. All sequenced viruses were clade 2.3.4.4b. Overall, 62 cases (89%) reported eye redness, 32 (46%) fever and 29 (41%) respiratory symptoms; 54 of 67 cases (81%) reported receiving antiviral treatment. Most illnesses were mild; however, four patie

SUBMITTER: Rolfes MA 

PROVIDER: S-EPMC12477757 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature