Glyphosate below no-observed-adverse-effect level exacerbates fatty liver hemorrhagic syndrome in laying hens.

ABSTRACT: Glyphosate (GLY) can disturb gut microbiota homeostasis through inhibiting bacterial shikimate pathway to pose a health challenge to animals and humans. But little information was reported about the influence of GLY on fatty liver hemorrhagic syndrome (FLHS) in laying hens, especially the exposure below no-observed-adverse-effect level. This study aimed to investigate the effects of GLY exposure on the progression of FLHS using a laying hen FLHS model induced by high-energy low-protein diet (HELPD). Ninety healthy Hyline brown laying hens were randomly allocated into 3 groups and subjected to the following feed for 6 weeks: Control group (fed with a basal diet), FLHS group (fed with HELPD), and FLHS + GLY group [fed with HELPD containing GLY (equal to 47 mg/kg body weight/d)]. Fresh feces

SUBMITTER: Liu J 

PROVIDER: S-EPMC12477941 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature