Non-invasive low-level red-light therapy for axial length control in pediatric extreme myopia.

ABSTRACT: Extreme myopia presents a notable clinical challenge in management, with existing approaches having limitations. Repeated low-level red-light therapy (RLRL) has shown potential for myopia control. This multi-center prospective study included 59 children (101 eyes, aged 3-16.3 years) with extreme (SER ≤ -10D) or high myopia (-6D to -9.75D), who underwent twice-daily RLRL for 12 months 55 children (94 eyes) completed the follow-up. After treatment, significant improvements were observed: spherical equivalent error increased by 0.549D (95% confidence interval [CI]: 0.430 to 0.668, p < 0.001), axial length shortened by 0.056 mm (95% CI: -0.087 to -0.025, p = 0.001), best-corrected visual acuity improved by 0.110 LogMAR, and choroidal thickness increased by 34.84 μm, with no adver

SUBMITTER: Tian L 

PROVIDER: S-EPMC12478052 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature