Association between COVID-19 vaccination and coronary heart disease: based on 2023 national health interview survey data.

ABSTRACT:

Background

Coronary heart disease (CHD) represents a critical cardiovascular ailment necessitating thorough investigation. This research endeavors to explore the potential link between COVID-19 vaccination and CHD, using data from the National Health Interview Survey (NHIS).

Methods

The study encompasses 20,906 participants from the 2023 NHIS cohort, and these participants were stratified into two groups: CHD patients and non-CHD individuals (controls). To determine the protective factors for CHD, both univariate and multivariate logistic regression analyses were carried out. Furthermore, Receiver Operating Characteristic (ROC) curves were plotted to assess the predictive performance of models that consider COVID-19 vaccination as a potential protective factor against CHD.

SUBMITTER: Mao J 

PROVIDER: S-EPMC12478238 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature