Microplastic abundance in placental chorionic villi detected by pyrolysis-gas chromatography/mass spectrometry in cases of spontaneous miscarriage during early pregnancy.

ABSTRACT:

Background

There is widespread concern regarding the effect of microplastics (MPs) on human reproductive health. The accumulation of MPs and their potential effect on adverse pregnancy outcomes must be determined, particularly from the perspective of the maternal-foetal interface during early gestation, because abnormal composition and metabolism of chorionic villi are closely related to early embryonic development. This study aimed to identify and quantify the mean mass concentrations and polymer types of MPs in human chorionic villi, and investigate the potential association between the abundance of MPs and spontaneous miscarriage.

Methods

Chorionic villi were collected from 31 participants in their first trimester, including normal carriage terminated for social factors (

SUBMITTER: Wang P 

PROVIDER: S-EPMC12478273 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature