Extensive Right Ventricular Involvement With Thrombus and Myocarditis: An Unanticipated Discovery in Advanced Hepatocellular Carcinoma.

ABSTRACT:

Background

Cardiac involvement in malignancies is rare, with right ventricular tumoral thrombus in hepatocellular carcinoma (HCC) without right atrial extension being exceptionally uncommon.

Case summary

A 54-year-old man with stage IV HCC experienced recurrent chest discomfort. Stress echocardiography detected an ill-defined inhomogeneous mass, and cardiac magnetic resonance identified right ventricular outflow tract obstruction, left ventricular septal infiltration, and acute-to-subacute myocarditis. Abdominal imaging showed tumor recurrence along with a large thrombus in the retrohepatic inferior vena cava. After multidisciplinary discussions, the patient opted for palliative comfort care.

Discussion

Systemic therapy for HCC such as atezolizumab-bevacizumab and len

SUBMITTER: Go WVP 

PROVIDER: S-EPMC12478496 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature