Physical activity is associated with exercise capacity among patients undergoing chemotherapy: A pilot randomized controlled trial.

ABSTRACT:

Introduction

Exercise intolerance is common among cancer patients undergoing active treatments. We conducted a pilot study in patients receiving potentially cardiotoxic therapies to investigate the impact of participation in a 6-month physical activity intervention (PAI) versus a healthy lifestyle education control intervention (HLI) on accelerometer-derived measures of PA (steps/day or minutes of moderate to vigorous PA [MVPA]/week) and whether these measures were associated with submaximal exercise capacity (6-minute walk distance [6MWD]).

Methods

Participants with breast cancer or lymphoma (n = 33) were randomized (2:1) into PAI or HLI groups. Exercise training was patient-centered, tailored by treatment and functional status. Objective assessments of PA (steps/day, MVPA/

SUBMITTER: Antonucci A 

PROVIDER: S-EPMC12478893 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature