Dual S-methoprene and Lysinibacillus sphaericus larvicide use leads to multiple independent, and not cross-resistance in Culex pipiens.

ABSTRACT: S-methoprene, an insect growth regulator, and Lysinibacillus sphaericus (Ls), an entomopathogenic bacterium, are important larvicides used to control Culex pipiens [L.] mosquitoes, the primary vector of West Nile virus, in the Chicago, IL USA region. Resistance to both agents has been documented globally including a report of resistance ratios greater than 100 to S-methoprene in the Chicago region. Laboratory studies have suggested the potential for unidirectional cross-resistance between S-methoprene and Ls, despite differing modes of action. Among wild populations of Cx. pipiens in the Chicago area, this study aimed 1) to assess resistance status to Ls, 2) confirm the presence of S-methoprene resistance ratios >100, 3) determine if higher S-methoprene resistance ratios are associated wit

SUBMITTER: Lopez K 

PROVIDER: S-EPMC12478903 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature