The Founders' 400 and Chicago Perinatal Origins of Disease study protocol: Following a prospective, longitudinal cohort from early pregnancy through two years of postnatal life.

ABSTRACT:

Introduction

The primary aim of the Chicago Perinatal Origins of Disease (CPOD) study is to characterize social, environmental, and biological exposures from early pregnancy through two years of postnatal life among a diverse cohort of mother-fetus/child dyads in the Chicago metropolitan community and to examine associations with pregnancy and early childhood health outcomes. This study is committed to ensuring the inclusion of participants historically underrepresented in perinatal research and most impacted by perinatal health inequities. CPOD is designed to align with key stakeholder and community input.

Methods

Approximately 400 pregnant people 8-28 weeks gestation and their neonates will be recruited into a longitudinal, prospective observational study enriched for part

SUBMITTER: Fisher SA 

PROVIDER: S-EPMC12478913 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature