Proteinuria in preterm neonates: influence of fetal growth restriction.

ABSTRACT:

Objective

To compare proteinuria in preterm neonates with fetal growth restriction-small for gestational age (FGR-SGA) against equally preterm but appropriate for gestational age (AGA) neonates.

Study design

Prospective, observational cohort study.

Results

Eighteen FGR-SGA neonates were compared with 18 AGA neonates (gestation; 29 ± 1 vs 29 ± 2 weeks, P = 0.8). Urine total protein (median [interquartile range]) in FGR-SGA was higher 370 [323, 573] vs 255 [193, 453] mg/L in AGA, P = 0.017 at first assessment (week one) and 565 [445, 743] vs 225 [135, 458] mg/L, P = 0.0011 at second assessment (week four). Urine protein creatinine ratio was 393 [250, 445] in FGR-SGA vs 227 [163, 367] mg/mmol in AGA, P = 0.029 at first assessment and 444 [368, 699] vs 240 [199, 411] mg/m

SUBMITTER: Sehgal A 

PROVIDER: S-EPMC12479344 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature