Leveraging artificial intelligence for prediction of pulmonary hemorrhage in preterm infants.

ABSTRACT:

Objectives

To identify clinical variables and indicators associated with pulmonary hemorrhage in preterm infants.

Methods

This case-control study included inborn infants <32 weeks. Data were collected in 12-h epochs from birth until hemorrhage onset or up to 72 h for controls. Machine learning used the Random Forest algorithm. Statistical analysis included T test and Mann-Whitney U test.

Results

Among 1133 screened infants, 35 had hemorrhage. Mean gestational age was 25.6 ± 1.6 weeks, birth weight 753 ± 224 g, and median onset of hemorrhage was 44.5 h. Affected infants more often required chest compressions and invasive ventilation. Machine learning (accuracy = 83%, AUC = 90%) identified repeated surfactant dosing and postnatal hypotension in the first 12 h of life as

SUBMITTER: Aly H 

PROVIDER: S-EPMC12479356 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature