Inter-Vertebral Signal Concordance Index is a Risk Factor for Osteoporotic Vertebral Compressed Fracture: Validated by Finite Element Analysis.

ABSTRACT: Study DesignRetrospective study.ObjectiveWe found that inter-vertebral signal concordance index (ISCI), as a novel factor, was significantly higher in the osteoporotic vertebral compressed fracture (OVCF) patients than non-OVCF patients in our previous retrospective study. In this study, we aim to validate the association between ISCI and OVCF using finite element analysis (FEA).MethodsFrom the non-fracture cohort of our previous diagnostic study, 18 female patients (50-75 years) with degenerative lumbar disease were selected. To minimize confounding factors affecting bone strength, paired patients were matched under criteria: 1. The same femoral neck T-score; 2. Age caliper of 4 years. FEA was adopted to predict vertebral bone strength under 500N compression and failure load for the paire

SUBMITTER: Cai C 

PROVIDER: S-EPMC12479464 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature