Head and neck related quality of life following glossectomy among tongue cancer patients: a systematic review and meta-analysis.

ABSTRACT:

Objective

This study synthesized previous studies to evaluate the post-operative head and neck-related quality of life (QoL) and pre-post operative change in the QoL of tongue cancer patients who underwent glossectomy.

Methods

Following the PRISMA guidelines, databases were searched on April 1, 2025, for relevant articles without date limits. Mean estimates and standardized mean differences were calculated for post-glossectomy and pre-post glossectomy changes in QoL, respectively. A random-effects model employing the restricted maximum likelihood was conducted. Effect heterogeneity was assessed using Q and I².

Results

A total of 56 studies (2,832 participants; mean [SD] age, 55.1 [7.5] years; 68.2% male) were included in the study. The meta-analysis estimat

SUBMITTER: Tundealao S 

PROVIDER: S-EPMC12479587 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature