Subjective psychiatric symptoms in post-acute autoimmune encephalitis: findings from the Australian autoimmune encephalitis consortium.

ABSTRACT:

Background and objectives

This study examined self-reported psychopathology in patients with autoimmune encephalitis (AE), and explored their relationship with clinical outcomes as measured by the modified Rankin Scale (mRS) and Clinical Assessment Scale in Autoimmune Encephalitis (CASE) scores.

Methods

Eighty-seven AE patients (49.43% female, mean age = 54.47 years, SD = 17.84) from the Australian Autoimmune Encephalitis Consortium completed the SPECTRA-Indices of Psychopathology, time-matched with CASE and mRS scores within six months of the assessments.

Results

On average, assessments occurred 12 months post-onset. Median CASE and mRS scores were 2, with 84.13% of patients scoring mRS ≤ 2. Mean SPECTRA scores were significantly elevated across multiple domains, ind

SUBMITTER: Ko KY 

PROVIDER: S-EPMC12479715 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature