First detection and genetic characterization of atypical Porcine pestivirus in pigs, Thailand.

ABSTRACT: Atypical Porcine Pestivirus (APPV) is an emerging pathogen in pigs. The virus causes diseases associated with neurological disorders, such as congenital tremors (CT) Type A-II in piglets, leading to economic losses in the swine industry. This study investigated an outbreak of Atypical Porcine Pestivirus (APPV) on a commercial pig farm in eastern of Thailand from November 2023 to July 2024. Our results showed APPV positive in 14.18% (39/275). APPV was highly detected in nursery pigs at 40.00% (12/30) with a statistically significant (P < 0.05) association between age and APPV infection. Thai-APPVs (n = 9) were characterized by complete genome sequencing. Phylogenetic analysis of the whole genome of APPVs showed that Thai-APPVs belonged to APPV-Clade I. Moreover, the Thai-APPVs were clustere

SUBMITTER: Shahid S 

PROVIDER: S-EPMC12479871 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature