A New Era in Tuberculosis Prevention and Treatment: Breakthroughs in Drug Development and Future Prospects.

ABSTRACT: Tuberculosis (TB) remains a significant global public health challenge, despite recent advances in drug development. However, a comprehensive and systematic overview of the current clinical trial landscape in TB prevention and treatment is still lacking. This study aims to systematically review recent breakthroughs in TB drug development, assess their scientific value and global impact, and provide valuable insights for clinicians and policymakers involved in TB control efforts. We systematically searched the INFORMA pharmaceutical database to identify 1041 clinical trial projects related to TB. Two independent researchers screened and extracted the data, and discrepancies were resolved through consultation with a third researcher. Inclusion criteria were: (1) trials explicitly focused on

SUBMITTER: Zhao CY 

PROVIDER: S-EPMC12480217 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature