Prevalence of GLUT1 overexpression in human cancers a systematic review and meta analysis.

ABSTRACT:

Background

The clinical significance of glucose transporter 1 (GLUT1) expression in cancers remains controversial due to inconsistent findings. This meta-analysis systematically evaluates the association between GLUT1 overexpression and its prevalence in cancer tissues, highlighting its potential role as a diagnostic biomarker.

Methods

A comprehensive search of MEDLINE and the Cochrane Library was performed up to May 30, 2024, to identify observational studies and RCTs examining the association of GLUT1 expression with its prevalence in cancer tissues. Data were analyzed using random-effects models, and results were presented as Risk Ratios (RRs) with 95% confidence intervals (CIs). Subgroup analyses were performed based on cancer types and geographical locations. This meta-

SUBMITTER: Yuan Q 

PROVIDER: S-EPMC12480296 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature