Age and sex affect circadian patterns of cardiac autonomic function.

ABSTRACT: The cardiovascular system exhibits circadian rhythmicity, responding to central and peripheral clocks. Sexual dimorphism and aging independently influence circadian rhythms and cardiac electrical activity, which the autonomic nervous system regulates. However, the extent to which sex and aging affect autonomic dynamics remains unclear. This study investigates their role in circadian cardiac autonomic activity in healthy subjects. Data from 51 males and 51 females with 24-hour Holter recordings were analyzed. Circadian patterns of Heart Rate Variability parameters, indicators of autonomic function, were assessed using fast Fourier transformation with 5-minute Blackman-Harris windows on artifact-free recordings. Fractal, multifractal, visual, and information methods were applied to evaluate

SUBMITTER: Buitrago-Ricaurte N 

PROVIDER: S-EPMC12480707 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature