Association of diabetic ketoacidosis and retinopathy in patients with type 2 diabetes: a nationwide cohort study.

ABSTRACT: Diabetic ketoacidosis (DKA) is the most common acute complication in people with diabetes. We aimed to assess the association of DKA with the risk of diabetic retinopathy (DR) and related ophthalmic interventions in individuals with type 2 diabetes (T2D). To ensure similar T2D management and severity at baseline between groups, we enrolled 1,007 T2D patients with and without DKA matched by anti-diabetic combination within the initial 3 months of diabetes diagnosis, gender, birth and diabetes diagnosis year in Taiwan National Health Insurance Research Database from 2000 to 2019. We employed Fine and Gray competing risk model to assess the risk of non-proliferative DR (NPDR), proliferative DR (PDR) and panretinal photocoagulation (PRP). Our results showed that patients with DKA had an increa

SUBMITTER: Chen YK 

PROVIDER: S-EPMC12480749 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature