Quantitative cardiovascular magnetic resonance myocardial perfusion can discriminate significant cardiac allograft vasculopathy: a multi-centre study.

ABSTRACT:

Aims

Cardiac allograft vasculopathy (CAV) is a significant complication that contributes to both morbidity and mortality after heart transplantation. The aim of this study was to (i) assess if quantitative cardiovascular magnetic resonance (CMR) myocardial perfusion could detect different stages of CAV and (ii) establish a myocardial perfusion reserve (MPR) cut-off for significant CAV.

Methods and results

Patients with a heart transplant who had performed a clinical CMR scan and invasive angiography at two centres in Sweden were included in the study (n = 110). Quantitative short-axis perfusion maps were acquired using single-bolus gadolinium contrast, dual-sequence perfusion imaging at rest and during stress. Global myocardial perfusion (MP) was averaged across all segments

SUBMITTER: Jablonowski R 

PROVIDER: S-EPMC12481015 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature