Making <i>in vitro</i> release and formulation data AI-ready: A foundation for streamlined nanomedicine development.

ABSTRACT: Machine learning and artificial intelligence (AI) is transforming the way pharmaceutical products are developed across drug discovery, process engineering, and pharmaceutics functions. AI for nanomedicine development is enabling faster and more accurate prediction of critical quality attributes (CQAs). However, the full potential of AI is limited by the quality and accessibility of data. Unlike adjacent fields such as the chemical sciences, the pharmaceutics domain lacks curated, open-access databases, particularly for nanomedicines. To address this, here we curate an open-access local database focused on liposomal formulations. The database includes formulation parameters, in vitro release (IVR) testing conditions, and digitised drug release data. By evaluating the entries in the d

SUBMITTER: Yanes D 

PROVIDER: S-EPMC12481109 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature