Use of real-world data and real-world evidence in NICE (UK) health technology appraisals of new therapeutics in oncology: a systematic review.

ABSTRACT:

Objectives

To quantify and describe the use of real-world data (RWD) in National Institute for Health and Care Excellence (NICE) oncology technology appraisal (TA) final appraisal determination documents.

Design

A systematic literature review was conducted on pharmaceutical NICE oncology TAs published between April 2000 and March 2024 (covering financial years 2000/2001 to 2023/2024 inclusive) extracted on 22 August 2023 (2000/2001 - 2022/2023) and 8 August 2024 (2023/2024).

Data sources

NICE TA final appraisal determination documents.

Eligibility criteria

All pharmaceutical oncology TAs published between April 2000 and March 2024 (financial years 2000/2001 to 2023/2024) that did not go on to be terminated.

Data extraction and synthesis

The data required

SUBMITTER: Tunaru F 

PROVIDER: S-EPMC12481278 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature