Cohort profile: trajectory of knee health in runners with and without heightened osteoarthritis risk (TRAIL) in Australia-prospective cohort study.

ABSTRACT:

Purpose

The TRAjectory of knee heaLth in runners (TRAIL) study is a prospective cohort study investigating the long-term knee health trajectories of runners with and without a heightened osteoarthritis risk. This study aims to describe the recruitment results and baseline characteristics of the TRAIL cohort.

Participants

Runners aged 18-50 years and running ≥3 times and ≥10 km per week on average in the past 6 months were eligible. Participants were recruited via running podcasts, running clubs and social media between July 2020 and August 2023. Data were collected at study enrolment and at a face-to-face baseline testing session, which occurred a median of 33 weeks (IQR 18 to 86 weeks) after enrolment. Follow-up data collection is ongoing.

Findings to date

Out of 462

SUBMITTER: De Oliveira Silva D 

PROVIDER: S-EPMC12481359 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature