Antipsychotics for Parkinson's disease: a protocol for a systematic review with network meta-analysis and trial sequential analysis.

ABSTRACT:

Introduction

Parkinson's disease is a neurological disease with a rising incidence and prevalence. Patients with Parkinson's disease may receive antipsychotics, for example, due to Parkinson's disease psychosis. Parkinson's disease psychosis is characterised by visual hallucinations and other psychotic symptoms. To date, no systematic review has evaluated the effects of antipsychotics in patients with Parkinson's disease. Therefore, this review aims to assess the beneficial and harmful effects of antipsychotics for Parkinson's disease.

Methods and analysis

This is a protocol for a systematic review. A search specialist will perform a search in major medical databases (eg, MEDLINE (Medical Literature Analysis and Retrieval System Online), EMBASE (Excerpta Medica database), CE

SUBMITTER: Petersen JJ 

PROVIDER: S-EPMC12481401 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature