Plasma Hepatic Transaminases and Incidence of Metabolic Syndrome Before Midlife in Military Adults: A CHIEF Cohort Study.

ABSTRACT:

Background

Plasma AST and ALT may reflect the nonalcoholic fatty liver disease (NAFLD) severity and have been associated with the risk of MetS in middle- or old-aged individuals.

Aims

This study aimed to examine the associations of plasma hepatic aspartate and alanine transaminases (AST and ALT) levels with incident metabolic syndrome (MetS) in young adults, which have not been verified before.

Objective

The goal of this study was to identify the association between plasma hepatic transaminases and the incidence of new-onset MetS among young adults.

Methods

There were 2,804 military men and women, with ages of 18-39 years, free of baseline MetS and any viral hepatitis in Taiwan in 2014. Incident MetS were followed in the annual military health examinations from

SUBMITTER: Liu FC 

PROVIDER: S-EPMC12481545 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature