Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.

ABSTRACT:

Introduction

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by sensory processing abnormalities, particularly in tactile perception, highlighting the need for objective screening methods beyond current subjective behavioral assessments.

Methods

This study developed a portable electro-tactile stimulation system with EEG to evaluate tactile processing differences in children with ASD (n=36) versus typically developing controls (n=36).

Results

Revealing significantly reduced ERP amplitudes at key processing stages: P200 at FP2 (F(1,70)=10.82, p=0.0454), N200 at F3 (F(1,70)=58.33, p<0.0001), and P300 at C4 (F(1,70)=45.62, p<0.0001). Topographic analysis identified pronounced group differences (>10ìV) across frontal, central, and parietal reg

SUBMITTER: Wang W 

PROVIDER: S-EPMC12481717 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature