Clinical value of metagenomic next-generation sequencing in diagnosis of Coxiella burnetii infection.

ABSTRACT:

Background

Metagenomic next-generation sequencing (mNGS) is a new pathogen detection technique, but the current experience of clinical application in Coxiella burnetii infection is relatively limited. This study aimed to investigate the clinical application value of mNGS in diagnosis of Coxiella burnetii infection.

Methods

We conducted a retrospective study that included patients with Coxiella burnetii infection detected by mNGS from December 2018 to August 2024. Their clinical information and mNGS test results were retrieved for analysis.

Results

A total of 70 patients with Coxiella burnetii infection were included in this study. The mean age of these patients was 43.5 years and the common clinical manifestations were fever (67/70, 95.7%), followed by headache (43/70

SUBMITTER: Luo Y 

PROVIDER: S-EPMC12481755 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature