Physical therapy versus conventional treatment for grade I and II acute ankle sprains: trial sequential analysis and meta-analysis.

ABSTRACT:

Background

This systematic review and meta-analysis evaluated the effectiveness of physiotherapy compared with conventional therapies for grade I and II acute ankle sprains.

Methods

Randomized controlled trials were identified through a comprehensive search of PubMed, Embase, and Web of Science databases. Eligibility criteria were defined using the PICOS framework. Analyses included forest plot analysis, subgroup analysis, sensitivity analysis, publication bias analysis, and Trial Sequential Analysis (TSA) using Review Manager (version 5.4), StataMP 17, and TSA 0.9.5.10 beta software.

Results

Ten RCTs involving 565 participants met the inclusion criteria. The physical therapy group had significantly lower post-treatment visual analog scale (VAS) scores for pain compar

SUBMITTER: Yang C 

PROVIDER: S-EPMC12481793 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature