Functional studies on methylation of the promoter region of the NR2E1 gene regulating adipocytes in beef cattle.

ABSTRACT:

Background

Methylation plays a pivotal role in the modulation of gene expression, with the occurrence of promoter and exon 1 methylation typically resulting in transcriptional repression. Lipid deposition constitutes a complex economic trait, with a multitude of genes participating in the regulatory cascade that shapes meat quality attributes. Nonetheless, the available data on genetic markers for meat quality and the corresponding functional genes remains scarce, posing significant challenges to the selection of superior breeds and the development of novel strains in beef cattle breeding programs.

Results

In the present investigation, we evaluated the methylation profile of the NR2E1 gene within the promoter CpG islands across three distinct breeds of beef cattle, and eluci

SUBMITTER: Feng L 

PROVIDER: S-EPMC12481836 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature