Retinal Perfusion and Injury in Sepsis and after Major Surgery.

ABSTRACT:

Objective

Assess retinal perfusion in sepsis, compared with uncomplicated postoperative care and healthy controls, and assess the effects of reduced perfusion on retinal structure and visual function.

Design

We conducted a prospective observational cohort study between March 2018 and December 2022, with follow-up measures collected 3 to 6 months after discharge.

Subjects

Twenty-four patients with sepsis were assessed in the intensive care unit (ICU) and 3 to 6 months later, 45 ICU control patients assessed during elective ICU admission after upper gastrointestinal cancer surgery, preoperatively, and 3 to 6 months later, and 15 healthy controls.

Testing

Assessments included retinal layer thickness using OCT, retinal perfusion using OCT angiography, and visual fu

SUBMITTER: Courtie E 

PROVIDER: S-EPMC12481890 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature