Assessing completeness of cancer family history in EHRs using genetically defined kinships: A cross-sectional study.

ABSTRACT:

Purpose

Family history (FHx) is the most widely available tool for reducing mortality and morbidity caused by heritable diseases. However, FHx may be inadequately documented. Our objective was to assess the rate at which cancers in patient relatives are documented as FHx in electronic health records (EHRs).

Methods

Our primary analysis included 903 Healthy Nevada Project participants who had cancer-diagnosed patient relatives removed by ≤2 degrees in a kinship analysis. The rate of successful EHR documentation of relatives' cancer type was quantified using generalized estimating equations.

Results

The population-average rate of cancer FHx documentation in the EHR was 45.2% (95% confidence interval [CI]: 42.0%-48.4%). The odds ratio (OR) for successful documentation wa

SUBMITTER: Kiser D 

PROVIDER: S-EPMC12481965 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature