Association of triglyceride-glucose index with risk of cardiovascular disease among patients with prediabetes: population based prospective cohort study.

ABSTRACT:

Background

The triglyceride-glucose (TyG) index was associated with an increased risk of cardiovascular disease (CVD) in patients with prediabetes. However, this association has not yet been evaluated in prospective studies. Hence, we aimed to investigate the association between the TyG index and the risk of incident CVD in patients with prediabetes.

Methods

Participants with prediabetes were enrolled from the Kailuan study and were followed up for clinical events until 2022. The exposure variable was TyG index. The primary outcomes were the incidence of CVD events, including ischemic heart disease and stroke, while the secondary outcomes were each specific type of CVD events. Cox proportional hazards regression models and restricted cubic spline analysis were used to calcul

SUBMITTER: Li M 

PROVIDER: S-EPMC12481991 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature