Cost-benefit analysis of universal screening for HCV infection in China: a Markov modelling study.

ABSTRACT:

Background

Hepatitis C virus (HCV) infection remains a major public health concern in China, contributing substantially to global HCV-related morbidity and mortality. In line with the World Health Organization (WHO) targets for HCV elimination by 2030, this study aimed to evaluate the long-term health and economic outcomes of universal HCV screening strategies in China.

Methods

A decision-analytic Markov model was developed to simulate HCV disease progression and healthcare costs over a 30-year time horizon (2026-2055). A total of 81 scenarios were assessed, including 80 universal screening strategies and a no-screening comparator. Strategies varied by age group (3-10, 20-60, 60-80, or 3-80 years), screening duration (10 or 30 years), and frequency (once in 2026, or repeated

SUBMITTER: Zhou D 

PROVIDER: S-EPMC12482108 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature