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A systematic review of the last two decades of NK cell-based clinical trials: state of the art of AML therapy.
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ABSTRACT:
SUBMITTER: Bakhtiyaridovvombaygi M
PROVIDER: S-EPMC12482124 | biostudies-literature | 2025 Sep
REPOSITORIES: biostudies-literature
Publications
A systematic review of the last two decades of NK cell-based clinical trials: state of the art of AML therapy.
BMC cancer 20250930 1
BACKGROUND: Acute myeloid leukemia (AML) remains a significant challenge in hematologic oncology, with high relapse rates and limited treatment options. Natural killer (NK) cells, as key effectors of innate immunity, have shown strong anti-leukemic activity, making them promising candidates for immunotherapy. Despite increasing clinical interest, a comprehensive evaluation of NK cell-based therapies in AML is still needed. METHODS: This systematic review follows the PRISMA guidelines to analyze ...[more]