The mortality of ischemic heart disease attributable to temperature variability: findings from the Global Burden of Disease Study 2021.

ABSTRACT:

Objective

To investigate the effect of temperature variability on ischemic heart disease (IHD) mortality and to provide a scientific basis for disease prevention and control strategies.

Methods

Age-standardized mortality rates (ASMRs) for temperature-related IHD were extracted from the Global Burden of Disease 2021 database. Joinpoint regression was used to analyze the trend of the ASMRs. Age-period-cohort (APC) models were used to analyze independent age, period and cohort effects. Bayesian APC model was used to project ASMRs into the next 30 years.

Results

From 1990 to 2021, ASMR of IHD related to low temperature decreased with time. However, ASMR related to high temperature demonstrated a gradual increase, though was still lower than ASMR related to low temperature

SUBMITTER: Liu A 

PROVIDER: S-EPMC12482138 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature