Immunology of vector-borne diseases: the role of immunopharmacology in controlling viral and parasitic infections.

ABSTRACT:

Background

Vector-borne diseases (VBDs) pose a significant global health threat, driven by complex interactions between pathogens, vectors, and host immune responses. Understanding the immunopharmacological mechanisms underlying these interactions is crucial for developing novel therapeutic and preventive strategies. This review explores the immunomodulatory effects of vector saliva, pathogen-induced immune evasion, and host-directed immunotherapies to provide a comprehensive perspective on immune regulation in VBDs.

Methods

A systematic review of peer-reviewed literature was conducted using databases such as PubMed, Scopus, and Web of Science. Studies on host immune responses, vector-mediated immunomodulation, and immunopharmacological interventions were included. Key theme

SUBMITTER: Abbasi E 

PROVIDER: S-EPMC12482234 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature