Short-term exposure to air pollution and risk of ischemic stroke requiring intravenous thrombolysis: a population-level analysis in Poland from the EP-PARTICLES study.

ABSTRACT:

Background

Air pollution is an important non-classical cardiovascular risk factor. Ischemic stroke (IS) is an increasing healthcare challenge, with the ageing population and associated presence of atrial fibrillation worldwide. In patients with IS, intravenous thrombolysis (IVT) is an effective treatment method within 4.5 hours from symptoms onset. Our aim was to assess the association between exposure to air pollution and IVT-treated IS, allowing for high temporal precision in exposure assessment.

Methods

We conducted a retrospective population-based cohort study including 5.4 million inhabitants in Eastern Poland in the Years 2011-20. IVT-treated IS patients were enrolled into this study based on ICD-10 and ICD-9 code (I63 with 99.101/99.102/99.103). To ensure high spatial

SUBMITTER: Swieczkowski M 

PROVIDER: S-EPMC12482355 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature