A link to the past: classical phage ISP infects the recently described Staphylococcus borealis species.

ABSTRACT:

Background

Staphylococcal infections, caused by a large variety of species within the Staphylococcus genus, are a threat to human health. Although antibiotics are the current choice of treatment for these infections, bacteriophage (phage) therapy has been used with success against Staphylococcus since the dawn of phage therapy. In 2020 a new coagulase-negative species named Staphylococcus borealis was described in Norway. In this study, we focused on understanding phage infections in S. borealis.

Methods

First, we predict the presence of prophages and phage-defence mechanisms in the genomes of a collection of twelve S. borealis strains by bioinformatics. We also attempted to isolate S. borealis-infecting phages from Norwegian samples and tested the host-range of three known

SUBMITTER: Sorensen AK 

PROVIDER: S-EPMC12482510 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature