Tongue myositis in dermatomyositis with anti-PM-Scl 75 antibody: two case reports.

ABSTRACT:

Background

Dermatomyositis (DM) is a heterogeneous disease characterized by skin rash and muscle weakness. Although tongue disorders have been documented in idiopathic inflammatory myopathies (IIM), biopsy-confirmed tongue myositis remains exceedingly rare, and no reports have been published in patients with DM.

Case presentation

This study describes two rare cases of anti-PM-Scl 75 antibody-positive dermatomyositis with tongue involvement and dysphagia. In case 1, muscle weakness and skin rash improved after the initial therapy. However, the patient developed tongue atrophy, severe pharyngeal dysphagia (Functional Oral Intake Scale (FOIS) level = 3) and dysarthria (Frenchay Dysarthria Assessment scale (FDA) score = 13) during the tapering of glucocorticoid. Escalating gluco

SUBMITTER: Sun C 

PROVIDER: S-EPMC12482549 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature