Use of the BIOFIRE^® FILMARRAY^® Pneumonia plus Panel to characterize the etiology of lower respiratory tract infections among hospitalized patients in Southern Province, Sri Lanka.

ABSTRACT:

Background

Lower respiratory tract infections (LRTIs) account for a heavy burden of illness in low- and middle-income country settings, but the etiology of these infections is often unknown. In this study, we applied the BIOFIRE^® FILMARRAY^® Pneumonia plus Panel, a multiplex polymerase chain reaction assay with bacterial, viral, and antibacterial resistance gene targets, on sputum samples to evaluate the etiology of community-acquired LRTI among hospitalized patients in southern Sri Lanka.

Methods

We enrolled children and adults hospitalized with LRTIs at a public tertiary care hospital in southern Sri Lanka from 2019 to 2021. Demographic and clinical data were collected, and a sputum sample for each patient was tested using the Pneumonia plus Panel. Ass

SUBMITTER: Weishampel ZA 

PROVIDER: S-EPMC12482574 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature