Gaps in the global health research landscape for mpox: an analysis of research activities and existing evidence.

ABSTRACT:

Background

Since December 2022, human cases of mpox in the Democratic Republic of the Congo (DRC) have risen at unprecedented rates. We identified a need for systematic mapping of the active research landscape and evidence, assessing their alignment with both local and global research priorities, to inform urgently needed research investments to support response efforts.

Methods

We conducted a mapping review of global research funding and international clinical trial registries and established a systematic rapid research needs appraisals platform to identify existing evidence gaps on mpox research. We analysed the alignment of these to established research categories and both local and globally identified mpox-specific research priorities.

Results

We identified 124 on

SUBMITTER: Furst R 

PROVIDER: S-EPMC12482760 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature