The safety and efficacy of finasteride for transgender men with androgenetic alopecia: a case series.

ABSTRACT:

Background

Testosterone replacement therapy is commonly used in transgender men for masculinization. One of the most common adverse effects of testosterone replacement therapy is androgenetic alopecia. In Japan, finasteride is approved exclusively for cisgender men and is not indicated for transgender men. The aim of this clinical trial was to evaluate the safety and efficacy of finasteride in transgender men with androgenetic alopecia.

Case presentation

This study included three transgender men (assigned female at birth, identifying as male), aged 44, 43, and 29 years. All participants were of Asian ethnicity. A clinical trial was conducted from October 2021 to December 2023. Transgender men aged 20-60 years who had not undergone hysterectomy, were undergoing testosterone r

SUBMITTER: Tominaga Y 

PROVIDER: S-EPMC12482827 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature