Registries on transcatheter edge-to-edge repair in heart failure: Current evidence and future perspectives.

ABSTRACT:

Aims

Secondary mitral regurgitation (SMR) and tricuspid regurgitation (TR) are the most common valvular heart diseases in patients with heart failure (HF). Transcatheter edge-to-edge repair (TEER) devices designed for treating MR and TR have been successfully tested in randomized controlled trials, but methodological issues have often challenged their interpretation. This manuscript aimed to provide an overview of TEER registries on SMR and TR in HF, highlighting their key features, describing clinical characteristics and outcomes of patients receiving these devices, and exploring the available data limitations.

Methods and results

PubMed, Web of Science, and EMBASE were searched for registries reporting on TEER in SMR or TR. Registries were excluded if single-centre and wit

SUBMITTER: Savarese G 

PROVIDER: S-EPMC12482848 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature