Influence of gestational weight gain and maternal depression on offspring BMI trajectory from birth to 3 years: A longitudinal mother-infant study.

ABSTRACT:

Objective

Gestational weight gain (GWG) is associated with offspring growth trajectories and early childhood obesity, but existing studies rarely account for maternal psychological status, which may confound or modify this association. This study aimed to evaluate the impact of GWG patterns on offspring body mass index-for-age Z score (BMI-Z) trajectories from birth to 3 years, adjusting for maternal depression and examining effect modification by depressive symptoms.

Methods

This mother-infant paired longitudinal cohort study was conducted between September 2019 and September 2024 at the Liuzhou Maternity and Child Healthcare Hospital. Data on maternal sociodemographic characteristics, health status, lifestyle factors, clinical and anthropometric measurements were collected

SUBMITTER: Zeng T 

PROVIDER: S-EPMC12483201 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature