The Impact of the First Trimester and Second Trimester Temperature, Air Pollutants, and Seasonal Variations on the Risk of Gestational Diabetes Mellitus in Twin Pregnancies.

ABSTRACT: Background: Recent studies have primarily focused on the impact of environmental factors on gestational diabetes mellitus (GDM) in singleton pregnancies, with limited research on their effects in twin pregnancies. This study investigates how seasonal variations and environmental exposures impact GDM incidence and its subtypes in twin pregnancies, a high-risk group. Methods: In this retrospective analysis of 3769 twin pregnancies, we categorized recruited participants into GDM and non-GDM groups. We examined the effect of the screening season on oral glucose tolerance test (OGTT) glucose values and the incidence of GDM and its subtypes. Multivariable logistic regressions adjusted for confounders assessed the impact of first and second trimester temperatures and air pollutants

SUBMITTER: Tang WZ 

PROVIDER: S-EPMC12483729 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature