Hashimoto's thyroiditis and thyroid hormone sensitivity in euthyroid individuals: their association with carotid plaque in northeast China.

ABSTRACT:

Background

Carotid plaque is a hallmark of systemic atherosclerosis, which underlies the pathology of cardiovascular and cerebrovascular events. Both thyroid hormones and Hashimoto's thyroiditis (HT) affect carotid plaque formation, but their impact on individuals with normal thyroid function remains unclear.

Methods

Clinical data, including demographics and medical history, were collected. Carotid and thyroid ultrasound, thyroid function tests, thyroid autoantibody measurements, and lipid profiles were performed. A retrospective analysis was conducted to explore the correlation of Hashimoto's thyroiditis (HT) and thyroid hormone sensitivity with carotid plaque risk in euthyroid individuals, with additional subgroup analyses.

Results

A total of 459 euthyroid patients

SUBMITTER: Wu Y 

PROVIDER: S-EPMC12483847 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature